The ultimate cause of Parkinson’s disease at the atomic level is toxic free radicals and their toxic metabolites.
Parkinson’s disease is a chronic- progressive central nervous system disease. The disease affects the human motor system, as manifested by involuntary movements, uncontrollable shaking, or vice versa, full stiffness. The cause of this disease has not been elucidated yet.
The first symptoms are often subtle and can be manifested differently in each person. There are three basic ones: increased muscle rigidity, slowness of movement (bradykinesia, hypokinesia) and tremors. Recently, we have included stability issues when standing.
In addition to these core symptoms, Parkinson’s disease has a wide range of the disability’s manifestations, from smell and sleep disorders, to psychiatric manifestations.
The ultimate cause of Parkinson’s disease at the atomic level is toxic free radicals and their toxic metabolites that damage certain brain cells. H2O2 (hydrogen peroxide) and TCA (tetracanoylphorbolacetate) are radicals capable of prematurely destroying brain cells. Carnosine is capable of preventing the formation of these radicals and thus protecting brain cells from damage.
Furthermore, the Lewy bodies in the brain of people suffering from Parkinson’s disease accumulate a substance called alpha-synuclein, which accelerates the process of the disease. Alpha-synuclein is formed in the state of oxidative stress and carnosine is able to reduce both the oxidative stress and the accumulation of alpha-synuclein. Therefore, carnosine has been recommended as a complementary treatment for Parkinson’s disease.